What question did this study set out to answer?

The aim is to assess tigecycline susceptibility in Acinetobacter spp. and evaluate breakpoint adjustments to lower error rates.

Multicenter Studies of Tigecycline Disk Diffusion Susceptibility Results for Acinetobacter spp

View Full Paper

Ask AI

Bookmark

Authors

Multicenter trial evaluates tigecycline susceptibility in Acinetobacter spp., adjusting breakpoints to reduce error rates.

The aim is to assess tigecycline susceptibility in Acinetobacter spp. and evaluate breakpoint adjustments to lower error rates.
Five-center study examining 103 Acinetobacter spp. isolates, focusing on MDR strains.
Comparison of broth microdilution and disk diffusion methods using tigecycline.
Adjustment of disk diffusion breakpoints from FDA criteria to improve accuracy.
Initial susceptibility assessment based on FDA criteria led to a 23.3% error rate.
Adjusting breakpoints to >=16 mm for susceptibility and <=12 mm for resistance reduced errors to 9.7%.
All errors noted were minor, indicating improved method reliability.

Jones et al. (2006) studied this question.

View Full Paper

Ask AI

Bookmark