What question did this study set out to answer?

Evaluate a time-dependent bone modeling and remodeling theory by simulating internal bone density distributions and functional adaptations in the adult proximal femur under changing daily loading histories.

September 1, 1990Journal of Orthopaedic Research®

An approach for time‐dependent bone modeling and remodeling—application: A preliminary remodeling simulation

View Full Paper

Ask AI

Bookmark

Authors

GBGary S. BeaupréUniversity of Bern TOTracy E. OrrUniversity of Bern DCD. R. CarterVA Palo Alto Health Care System

Discussion

Member takes

Implication

Finite element simulation demonstrates stress-driven density adaptation in the proximal femur, indicating mechanical loads regulate both bone morphogenesis and remodeling.

Key Points

Evaluate a time-dependent bone modeling and remodeling theory by simulating internal bone density distributions and functional adaptations in the adult proximal femur under changing daily loading histories.
Constructed two-dimensional finite element models of the adult proximal femur with fixed external geometry, initiating remodeling from a homogeneous solid bone structure.
Compared linear and trilinear (dead-zone nonlinearity) remodeling rate laws across periods of normal loading, reduced loading, and reinstated normal loading.
Simulations starting from uniform density under normal daily loading successfully generated a natural, physiological distribution of proximal femoral bone tissue.
Reduced mechanical loading induced regional bone atrophy, whereas reinstating normal loading stimulated generalized bone mass gains that yielded a slightly altered internal distribution compared to constant loading.

Cite This Study

Beaupré et al. (1990) studied this question.

synapsesocial.com/papers/6a712867e36a167817e2fc48 https://doi.org/10.1002/jor.1100080507

View Full Paper

Ask AI

Bookmark

Implication

Finite element simulation demonstrates stress-driven density adaptation in the proximal femur, indicating mechanical loads regulate both bone morphogenesis and remodeling.

An approach for time‐dependent bone modeling and remodeling—application: A preliminary remodeling simulation

Discussion

Member takes

Implication

Key Points

Cite This Study

An approach for time‐dependent bone modeling and remodeling—application: A preliminary remodeling simulation

Discussion

Member takes

Implication

Key Points

Cite This Study

Also Consider

Also Consider