Immunological Features in a Case of Subacute Sclerosing Panencephalitis Treated with Transfer Factor

A report is given on an attempt to treat a 16‐year‐old boy with rapidly progressing subacute sclerosing panencephalitis (SSPE) with soluble leukocyte transfer factor. Three separate injections, each containing transfer factor from lymphocytes of 450 ml venous blood, were given at three‐ to four‐month intervals. A remission, evidenced by clinical, immunological, and serological criteria, occurred and was sustained in the five months of observation after the last transfer factor injection. The close temporal relationship between start of therapy and onset of remission may suggest effects of transfer factor in this cast of SSPE, although a “spontaneous” remission cannot be wholly excluded.