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October 1, 1996Proceedings of the National Academy of SciencesOpen Access

Induction of Graves-like disease in mice by immunization with fibroblasts transfected with the thyrotropin receptor and a class II molecule.

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Authors

NSNaoki ShimojoChiba UniversityYKY KohnoChiba UniversityKYKensei YamaguchiThe Cancer Institute Hospital

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Cite This Study

Shimojo et al. (1996) studied this question.

synapsesocial.com/papers/6a712bbc660549caf2c5ce77https://doi.org/10.1073/pnas.93.20.11074
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Major histocompatibility complex class I gene expression in rat thyroid cells is regulated by hormones, methimazole, and iodide as well as interferon.1992 · 75 citations
  2. 2Overexpression of the extracellular domain of the thyrotrophin receptor in bacteria; production of thyrotrophin-binding inhibiting immunoglobulins1994 · 48 citations
  3. 3Characterization of Monoclonal Antibodies Derived from Lymphocytes from Graves' Disease Patients in a Cytochemical Bioassay for Thyroid Stimulators*1984 · 38 citations
  4. 4Generation and characterization of monoclonal antibodies to the human thyrotropin (TSH) receptor: antibodies can bind to discrete conformational or linear epitopes and block TSH binding.1995 · 39 citations
  5. 5Recombinant thyrotropin receptor and the induction of autoimmune thyroid disease in BALB/c mice: a new animal model.1994 · 59 citations