Acute Oliguria

Acute oliguria (excretion of less than 400 ml of urine per day) is often the earliest sign of impaired renal function and poses a diagnostic and management challenge to the clinician. Early identification of potentially reversible causes of acute oliguria and institution of appropriate therapy are crucial, since the therapeutic window is often small.1 Oliguria can have many causes. Some are overt and apparent, such as septic shock, whereas others are concealed and subtle, such as myoglobulin release or drug toxicity.2 The main functional derangement in patients with acute oliguria is a sudden and severe decrease in the glomerular filtration . . .