In this study, we proposed a dielectric-modulated (DM) junctionless negative capacitance FinFET (JLNC-FinFET) to achieve precise label-free electrical detection of biomolecules, including streptavidin (K=2.1), biotin (K=2.63), APTES (K=3.57), and Keratin (K=8), within the designated cavity region. The proposed approach employs variations in the threshold voltage for which the sensitivity (S VTH)has a maximum value of 15.2% for pyridine (K=12), serving as discerning metrics for detecting different neutral and charged biomolecules. The baseline junctionless (JL) FinFET, which is fabricated and characterized, in our previous publication, is opted for this study. Realizing the ferroelectric (FE) layer over its baseline counterpart offers a notableI ON/I OFFimprovement (~ 10^4)in JLNC-FinFET. The reliability concerns of metal gate granularities (MGGs) and line edge roughness (LER) have been considered to explore the impact on biomolecule detection, i.e., biosensor sensitivity. The results reveal that larger grain sizes (GSs) exacerbate work function (WF) variability, especially with biomolecules resembled by high-K cavities. Moreover, the LER significantly impacts device parameters, which worsens the detection of biomolecules with high-K and LER amplitudes. Thus, the proposed study is worth exploring to acquire the design guidelines for reliability-aware biosensors.
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Gandhi et al. (2024) studied this question.
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