Population
18-day-old chick embryos
Comparison
Incubation at 90 degrees F during the last week… vs Incubation at normal temperature of 100 degrees F
Design
Preclinical
Follow-up
1 week (last week of incubation)
Authors
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Chick embryo data warrant no clinical extrapolation; leaves open temperature effects on myocardial ultrastructure in mammals.
Reduced environmental temperature during incubation increases the number of annulate lamellae in the myocardium of chick embryos.
Merkow et al. (1966) studied this question.
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