Why the study?
Does decreased heart rate recovery and chronotropic incompetence correlate with exercise capacity and prognosis in patients with idiopathic pulmonary arterial hypertension?
Does decreased heart rate recovery and chronotropic incompetence correlate with exercise capacity and prognosis in patients with idiopathic pulmonary arterial hypertension?
Decreased heart rate recovery and chronotropic incompetence during exercise testing may serve as markers of poor prognosis and limited exercise capacity in IPAH patients.
May refine IPAH risk stratification after CPET; leaves open whether it improves outcomes over validated scores.
We show by this study that a decrease in HRR1 in IPAH patients is associated with severe limitation of exercise capacity. HRR1 < 16 beats and CI just after completion of a CPET could be an indicator of poor prognosis.
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Wu et al. (2017) studied this question.
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