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Clinical study demonstrates blood-aqueous barrier recovery tracks disease resolution in posterior uveitis, indicating fluorophotometry objectively quantifies treatment response.
Twenty patients with posterior uveitis were studied by anterior segment fluorophotometry to determine whether there was a relationship between the degree of breakdown of the blood-aqueous barrier and the clinical recovery of posterior uveitis. In individual eyes the degree of breakdown and recovery of the blood-aqueous barrier (as measured by changes in the anterior chamber fluorescein concentration) followed the resolution and relapse of disease making it possible to quantify the ocular response to treatment.
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Ferguson et al. (1992) studied this question.
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