Automatic calculation of myocardial external efficiency using a single 11C-acetate PET scan

Figures

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  Figure 1. Correlation (A, C) and Bland Altman plot (B, D) of forward cardiac output (A, B) and left ventricular mass (C, D) based on CMR (FCOPET-CMR and LVMPET-CMR) and PET (FCOPET and LVMPET). Black and gray lines indicate the line of identity and the linear fit in (A, C) and the mean difference and the 95% confidence interval in (B, D). RPC: repeatability coefficient. Red: healthy controls (n = 10), blue: AVS patients (n = 33), green: MVR patients (n = 20)

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  Figure 2. Correlation (A, C) and Bland Altman plot (B, D) of external work (A, B) and total energy use (C, D) based on CMR (EWPET-CMR and TEPET-CMR) and PET (EWPET and TEPET). Black and gray lines indicate the line of identity and the linear fit in (A, C) and the mean difference and the 95% confidence interval in (B, D). RPC, repeatability coefficient. Red: healthy controls (n = 10), blue: AVS patients (n = 33), green: MVR patients (n = 20)

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  Figure 3. Correlation (A) and Bland Altman plot (B) of myocardial external efficiency based on a combined PET-CMR protocol (MEEPET-CMR) and PET-only (MEEPET). Black and gray lines indicate the line of identity and the linear fit in (A) and the mean difference and the 95% confidence interval in (B). RPC: repeatability coefficient. Red: healthy controls (n = 10), blue: AVS patients (n = 33), green: MVR patients (n = 20)

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  Figure 4. Mean ± SD and individual values for EWPET (A), TEPET (B) and MEEPET (C) for all three groups. *, **, *** indicate significance level of < 0.05, < 0.01, and < 0.001, respectively

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  Figure 5. Correlation of mean pressure gradient over de aortic valve and MEE derived using PET-CMR (A) and PET-only (B) for AVS patients

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  Figure 6. Correlation of CMR-derived regurgitant fractions and MEE derived using PET-CMR (A) and PET-only (B) for MVR patients. RF, regurgitant fraction

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  Figure 7. Mean ± standard deviation of MEEPET-CMR (A) and MEEPET (B) per NYHA heart failure class. *, **, and *** denote a P value below 0.05, 0.01, and 0.001, respectively