Why the study?
Does direct percutaneous transluminal coronary angioplasty improve infarct artery patency, ventricular function, and clinical outcome in patients with acute myocardial infarction?
Does direct percutaneous transluminal coronary angioplasty improve infarct artery patency, ventricular function, and clinical outcome in patients with acute myocardial infarction?
Direct angioplasty shows advantages in infarct artery patency, ventricular function, and clinical outcomes for the treatment of acute myocardial infarction.
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May support direct angioplasty in acute MI; hypothesis-generating and requires randomized confirmation before practice change.
As a primary treatment modality for acute myocardial infarction, direct percutaneous transluminal coronary angioplasty has traditionally been reserved for hemodynamically compromised patients and those with contraindications to thrombolytic therapy. However, both basic and clinical studies have recently pointed out the advantages of direct angioplasty with regards to infarct artery patency, ventricular function, and clinical outcome. This review highlights and summarizes recent work pertaining to the general application of direct angioplasty for the treatment of acute myocardial infarction.
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Stewart et al. (1995) studied this question.
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