Why the study?
Does atherosclerosis increase perfusion of the aortic wall by vasa vasorum in cynomolgus monkeys?
Population
Normal and atherosclerotic cynomolgus monkeys
Comparison
Atherosclerosis disease model and adenosine… vs Normal cynomolgus monkeys
Design
Preclinical
Authors
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Suggests compensatory vasa vasorum proliferation in primate atherosclerosis; leaves open human translation and therapeutic relevance.
Does atherosclerosis increase perfusion of the aortic wall by vasa vasorum in cynomolgus monkeys?
Atherosclerosis is associated with increased perfusion of the aortic wall by vasa vasorum, likely due to proliferation of new vessels as a compensatory response.
Heistad et al. (1981) studied this question.
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