July 1, 1992Psychosomatic Medicine
Major depression in coronary artery disease patients with vs. without a prior history of depression.
Why the study?
Are there systematic differences in clinical and demographic characteristics between CAD patients with major depression who have a prior history of depression versus those who do not?
Population
39 patients with recently diagnosed coronary artery disease who met DSM-III-R criteria for major depression
Comparison
Prior history of major depression vs No prior history of major depression
Design
Cross-sectional
Authors
Discussion
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Member takes
Implication
Prior MD history marks a distinct CAD-depression subgroup; hypothesis-generating and should not yet change practice.
Structured PICO
Are there systematic differences in clinical and demographic characteristics between CAD patients with major depression who have a prior history of depression versus those who do not?
P
Population
39 patients with recently diagnosed coronary artery disease (CAD) who met DSM-III-R criteria for major depression (MD)
I
Intervention
Prior history of major depression
C
Comparator
No prior history of major depression
O
Outcome
Systematic differences in demographic and clinical characteristics (sex, depression severity, age, CAD severity)
CAD patients with major depression may represent two distinct subtypes based on prior depression history, with those having prior depression being more likely female and having more severe depression.
Cite This Study
Freedland et al. (1992) studied this question.