hERG IC10 provides a direct index of QT liability that leverages Hill slope differences to improve prediction of ΔΔQTc liabilities near critical hERG inhibition of ~10%.
Absolute Event Rate: 0% vs 0%
provides a direct index of QT liability, which takes advantage of differences in Hill slope to improve prediction of ΔΔQTc liabilities near critical hERG inhibition of ∼10%.
Edwards et al. (Mon,) reported a other. hERG IC10 provides a direct index of QT liability that leverages Hill slope differences to improve prediction of ΔΔQTc liabilities near critical hERG inhibition of ~10%.