Is PESI a reliable tool for predicting early mortality in acute pulmonary embolism? Real-life evidence from a single-center study

Recent publications on pulmonary thromboembolism (PTE) have reported signs of right ventricular dysfunction (RVD) on echocardiography or computed tomography (CT) in approximately 34% of patients classified as low risk according to the Pulmonary Embolism Severity Index (PESI). (1)However, these patients are not represented in the early mortality risk assessment tables of current guidelines. (2,3)We defined this subgroup as the so-called "missing group" and aimed to evaluate their clinical characteristics and 30-day mortality outcomes, given the uncertainty surrounding their risk classification.