Why the study?
Rational perioperative anesthetic drug selection and administration require knowledge of how obesity interacts with those drugs amid the globally increasing prevalence of obesity.
This review summarizes the pharmacokinetics, pharmacodynamics, and clinical application of perioperative anesthetic medications for enhanced recovery in obese patients undergoing bariatric surgery.
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May inform perioperative anesthetic selection in obesity; leaves open prospective validation for enhanced recovery protocols.
The prevalence of obesity is increasing globally. Rational perioperative anesthetic drug selection and administration require knowledge of how obesity interacts with those drugs. In this review, we summarize different aspects of the anesthetic agents, including pharmacokinetics (PK), pharmacodynamics (PD) and clinical application of the most commonly used medications with particular focus on the enhanced recovery of the obese patient.
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Falcão et al. (2019) studied this question.
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