Why the study?
Does replacement of the ICD generator with a sensing filter suppress T-wave oversensing in a patient with long QT syndrome?
Does replacement of the ICD generator with a sensing filter suppress T-wave oversensing in a patient with long QT syndrome?
In patients with long QT syndrome and an ICD, T-wave oversensing causing inappropriate pacing inhibition can be resolved by replacing the generator with one featuring a specific T-wave sensing filter.
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May resolve TWOS-induced pacing inhibition in LQTS; hypothesis-generating and requires prospective confirmation before broader adoption.
Inappropriate inhibition of atrial pacing due to T-wave oversensing (TWOS) was observed in a patient presenting with congenital long QT syndrome, treated with an implantable cardioverter defibrillator (ICD) and beta-adrenergic blocker. Development of TWOS was associated with further QT interval prolongation in the absence of amplitude changes in the intracardiac T and R waves. Replacement of the ICD generator with a sensing filter designed to attenuate the intracardiac T wave suppressed TWOS and normalized the pacing functions.
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Iijima et al. (2011) studied this question.
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