Why the study?
Does aortic arch pulse wave velocity predict subsequent white matter hyperintensity volume independent of other cardiovascular risk factors in a multiethnic population?
Population
1270 participants from the multiethnic probability-based Dallas Heart Study
Design
Cohort
Follow-up
7 years
Authors
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May inform vascular risk assessment; leaves open whether modifying aortic stiffness alters WMH progression.
Does aortic arch pulse wave velocity predict subsequent white matter hyperintensity volume independent of other cardiovascular risk factors in a multiethnic population?
Aortic arch pulse wave velocity measured by phase-contrast MRI is a strong independent predictor of subsequent white matter hyperintensity volume, suggesting a link between central aortic stiffness and cerebral microvascular disease.
King et al. (2013) studied this question.
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