What question did this study set out to answer?

To evaluate whether targeting normal versus supranormal oxygen delivery in major trauma resuscitation reduces crystalloid volume requirements, intra-abdominal hypertension, and abdominal compartment syndrome.

June 1, 2003Archives of Surgery

Supranormal Trauma Resuscitation Causes More Cases of Abdominal Compartment Syndrome

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Authors

ZBZsolt J. BaloghJohn Hunter Hospital

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Implication

Cohort study reveals higher rates of abdominal compartment syndrome under supranormal resuscitation in major trauma patients, indicating standard fluid goals improve survival.

Key Points

To evaluate whether targeting normal versus supranormal oxygen delivery in major trauma resuscitation reduces crystalloid volume requirements, intra-abdominal hypertension, and abdominal compartment syndrome.
Retrospective analysis of a prospective trauma database in a 20-bed intensive care unit at a regional level I trauma center.
Compared major trauma patients resuscitated to a supranormal oxygen delivery index (DO2I ≥600 mL/min/m², n=85) versus a normal oxygen delivery index (DO2I ≥500 mL/min/m², n=71) during their first 24 hours.
Assessed crystalloid infusion volume, gastric tonometry (GAPCO2), intra-abdominal hypertension, abdominal compartment syndrome, multiple organ failure, and mortality.
Patients in the supranormal resuscitation group received significantly more lactated Ringer solution (13 ± 2 vs 7 ± 1 L; P < .05) and had elevated GAPCO2 levels (16 ± 2 vs 7 ± 1 mm Hg; P < .05).
Incidence of intra-abdominal hypertension (42% vs 20%; P < .05) and abdominal compartment syndrome (16% vs 8%; P < .05) was significantly higher with supranormal resuscitation.
Multiple organ failure (22% vs 9%; P < .05) and ICU mortality (27% vs 11%; P < .05) were both significantly greater in the supranormal group compared to the normal resuscitation group.

Cite This Study

Zsolt J. Balogh (2003) studied this question.

synapsesocial.com/papers/6a7140706ceb2bbd16e01b28 https://doi.org/10.1001/archsurg.138.6.637

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Implication

Cohort study reveals higher rates of abdominal compartment syndrome under supranormal resuscitation in major trauma patients, indicating standard fluid goals improve survival.

Supranormal Trauma Resuscitation Causes More Cases of Abdominal Compartment Syndrome

Discussion

Member takes

Implication

Key Points

Cite This Study

Supranormal Trauma Resuscitation Causes More Cases of Abdominal Compartment Syndrome

Discussion

Member takes

Implication

Key Points

Cite This Study

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