Why the study?
Does coronary artery bypass grafting without cardiopulmonary bypass provide favorable clinical outcomes and graft patency in patients requiring surgical revascularization?
Does coronary artery bypass grafting without cardiopulmonary bypass provide favorable clinical outcomes and graft patency in patients requiring surgical revascularization?
While off-pump CABG provides favorable early postoperative outcomes, the low late patency rate of saphenous vein grafts suggests a need to reevaluate patient selection or surgical technique.
Low hospital mortality supports off-pump CABG feasibility; leaves open long-term saphenous vein graft patency concerns requiring prospective trials.
Between March 1994 and April 1998, 2869 patients underwent coronary artery bypass grafting at our institution. Of these, 415 (14.5%) with a mean age of 54.4 ± 9.9 years were operated on without cardiopulmonary bypass. Internal thoracic artery was used in 402 cases (97%) and the left anterior descending artery was revascularized in all except 1. Distal anastomoses ranged from 1 to 3, with a mean of 1.45 ± 0.58. Major postoperative complications comprised reoperation because of internal thoracic artery spasm in 1 patient, lower extremity ischemia due to intraaortic balloon pumping in 1 patient, revision for excessive bleeding in 3, and perioperative myocardial infarction in another 3. Hospital mortality was 1.2% (5 deaths). Coronary angiography was performed in 38 patients, 1 to 44 months postoperatively. Examination of 56 distal anastomoses revealed a patency rate of 86.1% for internal thoracic artery grafts and 55% for saphenous vein grafts. It was concluded that coronary bypass surgery without cardiopulmonary bypass gave favorable results in the early postoperative period. However, considering the late graft patency rates, either patient selection or the technique should be reevaluated.
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Tezcaner et al. (2000) studied this question.
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