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November 10, 2023Open Access

Reduced Post-Ablation Chest Pain with Active Esophageal Cooling

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Why the study?

Post-ablation chest pain is common after RF PVI for AF, and active esophageal cooling has pleiotropic effects that may mitigate inflammation and reduce post-ablation chest pain.

Does active esophageal cooling reduce post-ablation chest pain in patients undergoing radiofrequency pulmonary vein isolation for atrial fibrillation?

Population

183 patients undergoing RF PVI for AF

Comparison

Post-adoption of active esophageal cooling vs pre-adoption

Design

Registry-based pre-post cohort study

Authors

WZWilliam ZagrodzkyASA. SmallCJChristopher Joseph

Discussion

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Overview

Active esophageal cooling may reduce post-ablation chest pain; leaves open its role in routine AF ablation.

Structured PICO

Does active esophageal cooling reduce post-ablation chest pain in patients undergoing radiofrequency pulmonary vein isolation for atrial fibrillation?

P
Population
183 patients undergoing radiofrequency (RF) pulmonary vein isolation (PVI) ablation for the treatment of atrial fibrillation (AF) at a community hospital.
I
Intervention
Active esophageal cooling during RF ablation, followed by 2 days of prophylactic sucralfate and pantoprazole (n=93).
C
Comparator
No active esophageal cooling during RF ablation, followed by 2 weeks of daily prophylactic sucralfate and pantoprazole (n=90).
O
Outcome
Incidence of post-ablation chest painpatient reported

The adoption of active esophageal cooling during radiofrequency ablation for atrial fibrillation was associated with a complete elimination of post-ablation chest pain, compared to a 45.6% incidence in historical controls.

Cite This Study

Zagrodzky et al. (2023) studied this question.

synapsesocial.com/papers/6a7143755d37378ac1de6ad1https://doi.org/10.22541/au.169963495.52356965/v1
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