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August 1, 2018EClinicalMedicineOpen Access

Changing the System - Major Trauma Patients and Their Outcomes in the NHS (England) 2008–17

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Authors

CMChristopher G. MoranNottingham University Hospitals NHS TrustFLFiona LeckyDepartment of Health and Social CareOBOmar BouamraUniversity of Manchester

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Overview

Longitudinal cross-sectional study demonstrates improved risk-adjusted survival in severe trauma patients following regional system restructuring, indicating benefits of centralized trauma care.

Key Points

  • To evaluate the impact of reorganizing trauma care into regional networks with designated Major Trauma Centres on clinical processes and patient survival across England.
  • Conducted a longitudinal series of annual cross-sectional studies from April 2008 to March 2017 using national clinical audit data in England.
  • Analyzed N = 110,863 patients with an Injury Severity Score ≥ 9 admitted to 35 consistently submitting hospitals.
  • Assessed changes in care delivery and outcomes using case-mix risk-adjusted survival models and interrupted time series analysis around the April 2012 system reconfiguration.
  • Overall unadjusted mortality was 9.2% (10,247/110,863 deaths) among patients with an ISS ≥ 9, showing no change in raw mortality over time.
  • Case-mix adjusted odds of survival from severe injury increased by 19% (95% CI, 3%–36%) across the 9-year study period.
  • Interrupted time series analysis demonstrated a significant post-intervention slope increase after April 2012 (+0.08% excess survivors per quarter, p = 0.023).

Cite This Study

Moran et al. (2018) studied this question.

synapsesocial.com/papers/6a7144bf75498292b70abfbdhttps://doi.org/10.1016/j.eclinm.2018.07.001
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