Why the study?
Does a positive cerebrospinal fluid enterovirus PCR test result reduce the length of hospitalization and duration of antibiotic use in infants ≤ 90 days of age with suspected aseptic meningitis?
Population
478 infants ≤ 90 days of age with suspected aseptic meningitis evaluated at an urban, tertiary-care…
Comparison
Positive cerebrospinal fluid enterovirus… vs Negative cerebrospinal fluid enterovirus…
Design
Cohort
Authors
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Supports shorter stays and antibiotic use with positive CSF enterovirus PCR; leaves open prospective validation before routine adoption in young infants.
Does a positive cerebrospinal fluid enterovirus PCR test result reduce the length of hospitalization and duration of antibiotic use in infants ≤ 90 days of age with suspected aseptic meningitis?
Routine CSF enterovirus PCR testing in young infants with suspected aseptic meningitis can significantly reduce hospital length of stay and antibiotic duration.
King et al. (2007) studied this question.
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