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July 16, 2015Journal of Applied PhysiologyOpen Access

Methodological comparison of active- and passive-driven oscillations in blood pressure; implications for the assessment of cerebral pressure-flow relationships

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Why the study?

Do active squat-stand maneuvers compared to passive OLBNP improve the reproducibility of cerebral pressure-flow dynamic assessments in adults?

Population

19 adults, comprising younger (n=10; 25 ± 3 yr) and older (n=9; 66 ± 4 yr) adults.

Comparison

Active-driven oscillations in blood pressure via… vs Passive-driven oscillations via oscillatory…

Design

Other

Authors

JSJonathan D. SmirlUniversity of CalgaryKHKeegan HoffmanUniversity of British ColumbiaYTYu‐Chieh TzengUniversity of Otago

Discussion

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Implication

Active squat-stand may outperform OLBNP for reproducible BP oscillations; leaves open optimal protocols for cerebral autoregulation research.

Structured PICO

Do active squat-stand maneuvers compared to passive OLBNP improve the reproducibility of cerebral pressure-flow dynamic assessments in adults?

P
Population
19 adults, comprising younger (n=10; 25 ± 3 yr) and older (n=9; 66 ± 4 yr) adults.
I
Intervention
Active-driven oscillations in blood pressure via squat-stand maneuvers at 0.05 and 0.10 Hz.
C
Comparator
Passive-driven oscillations via oscillatory lower-body negative pressure (OLBNP) maneuvers and spontaneous data.
O
Outcome
Between-day reproducibility of cerebral pressure-flow dynamics (coherence, gain, normalized gain, phase) measured by within-subject coefficient of variation (CoV).surrogate

Active squat-stand maneuvers provide more reliable and reproducible assessments of cerebral pressure-flow dynamics compared to passive OLBNP or spontaneous measurements.

Cite This Study

Smirl et al. (2015) studied this question.

synapsesocial.com/papers/6a714a99ac440176ef29f940https://doi.org/10.1152/japplphysiol.00264.2015
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