Why the study?
The comparative effectiveness and safety of new-generation transcatheter aortic valve implantation devices remained uncertain.
Does the Evolut device compared to the Portico device improve clinical outcomes or reduce complications in patients undergoing transcatheter aortic valve implantation for severe aortic stenosis?
Population
233 patients undergoing TAVI for severe aortic stenosis
Comparison
Evolut vs Portico devices
Design
Prospective registry-based propensity-score-adjusted study
Follow-up
6 ± 7 months
Authors
Loading...
No significant differences between devices after adjustment; leaves open need for randomized head-to-head TAVI trials.
Does the Evolut device compared to the Portico device improve clinical outcomes or reduce complications in patients undergoing transcatheter aortic valve implantation for severe aortic stenosis?
The Evolut and Portico devices offer similar acute and mid-term safety and effectiveness for TAVI, though the Evolut device is associated with a higher risk of permanent pacemaker implantation.
Giordano et al. (2019) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: