Population
Mice carrying a dominant negative mutation in the KCNQ5 pore (Kcnq5(dn/dn) mice)
Design
Preclinical
Authors
Loading...
No clinical implications from mouse data; leaves open KCNQ5 validation in human hippocampal physiology.
KCNQ5 channels contribute to afterhyperpolarization currents in the mouse hippocampus in a cell type-specific manner.
Tzingounis et al. (2010) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: