Why the study?
Does ibuprofen reduce fever in children compared to aspirin, paracetamol, aminophenazone, and indomethacin?
Population
79 children (age 3 months to 13 years) with a rectal temperature above 38.5 degrees C
Comparison
Ibuprofen 6 mg/kg vs Aspirin, paracetamol, aminophenazone, and…
Design
Case_series
Follow-up
6 hours
Authors
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May support ibuprofen for pediatric fever; hypothesis-generating from Level 5 evidence and requires randomized confirmation before practice change.
Does ibuprofen reduce fever in children compared to aspirin, paracetamol, aminophenazone, and indomethacin?
Ibuprofen at 6 mg/kg is an effective antipyretic in children, demonstrating twice the fever-reducing effect of aspirin or paracetamol.
Similä et al. (1976) studied this question.
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