Why the study?
Does preoperative IABP support reduce mortality and morbidity in patients with left main coronary stenosis undergoing revascularization surgery?
Does preoperative IABP support reduce mortality and morbidity in patients with left main coronary stenosis undergoing revascularization surgery?
Preoperative IABP support appears to be a safe and effective adjunct to prevent hemodynamic deterioration and mortality during anesthesia induction in patients with left main coronary stenosis undergoing surgery.
Does not support routine preoperative IABP; leaves open mortality benefit in left main stenosis surgery pending randomized trials.
Twenty-six patients with left main coronary (LMC) stenosis were operated upon with preoperative intra aortic balloon pump (IABP) support. There was no mortality, and no morbidity attributable to the balloon catheter. The most delicate facet of revascularization surgery in this entity is the pre-cardiopulmonary bypass phase including anesthesia induction during which blood pressure fluctuation may further diminish severely compromised coronary flow. Although systolic pressure dropped to below 100 mm Hg in 50% of patients during induction, there were only two patients with electrocardiographic evidence of perioperative myocardial infarction, and only one who needed rantic institution of cardiopulmonary bypass just after induction. Perioperative logistics were quite trouble free in all 26 patients, in marked contrast to 5 LMC patients operated upon prior to our preoperative IABP concent; 3 of these deteriorated upon induction, with two deaths resulting. Preoperative IABP is a reasonable supportive adjunct in surgery for LMC stenosis.
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Cooper et al. (1977) studied this question.
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