This review summarizes the experimental evidence regarding the renin-angiotensin-aldosterone axis in the pathophysiology, diagnosis, and management of renal hypertension.
May inform RAAS strategies in renal hypertension; leaves open validation through clinical trials.
The increased understanding of the mechanisms leading to production of renal hypertension, and in particular the recognition of the renin-angiotensin-aldosterone axis as an integrated capacity-volume system for the control of arterial blood pressure, now allows a rational approach to the diagnosis and management of patients suffering from this disease. In this brief review some of the experimental evidence behind this rational approach is presented.
No takes yet. Share an insight, caveat, or question.
G. J. A. Clunie (1977) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: