Neurological complications remain a significant problem after pediatric cardiac surgery, with multiple proposed etiologic factors including altered cerebral blood flow and metabolism.
Warrants heightened perioperative vigilance in pediatric cardiac surgery; leaves open targeted interventions for cerebral hemodynamics.
Although mortality rate after cardiac surgery has been drastically reduced, neurological complications remain a significant problem. Several etiologic factors have been proposed, including previous unrecognized neurological abnormality, embolic events, hypoxic insult, low cardiac output, systemic inflammatory response, and altered cerebral blood flow (CBF) and metabolism. Cerebral ischemia can occur when cerebral oxygen is insufficient to meet the global or regional cerebral oxygen consumption. Cerebral circulation is normally regulated by several complex mechanisms, such as metabolic stimuli, chemical stimuli, perfusion pressure, and neural stimuli [1].
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David C. Bellinger (2000) studied this question.
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