Why the study?
Does aspirin alone reduce all-cause death and vascular events in patients with confirmed cardiovascular disease?
Population
Patients with confirmed cardiovascular disease, categorized into coronary artery disease, cerebrovascular…
Comparison
Aspirin alone vs Placebo
Design
Meta-analysis, randomized, placebo-controlled
Authors
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Supports aspirin for secondary prevention in CAD, CRVD, and PAD; confirms all-cause mortality and vascular event reductions.
Does aspirin alone reduce all-cause death and vascular events in patients with confirmed cardiovascular disease?
Aspirin significantly reduces the risk of all-cause death and vascular events in patients with established CAD, CRVD, and PAD, though it increases the risk of major bleeding.
Lièvre et al. (2009) studied this question.
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