Why the study?
Clinical characteristics and outcomes were assessed for women undergoing concurrent valve replacement and caesarean section for severe rheumatic mitral valve disease with refractory heart failure.
Is concurrent valve replacement and caesarean section safe and effective in pregnant women with severe rheumatic mitral valve disease and refractory heart failure?
Is concurrent valve replacement and caesarean section safe and effective in pregnant women with severe rheumatic mitral valve disease and refractory heart failure?
Concurrent valve replacement and caesarean section is a feasible option for pregnant women with severe rheumatic mitral valve disease and refractory heart failure who are unsuitable for minimal access interventions.
Answers are grounded in this paper and cite their sources.
May warrant individualized consideration in refractory cases; leaves open need for multicenter prospective data on outcomes.
Objective: To assess clinical characteristics and outcomes of women who underwent concurrent valve replacement with caesarean section for severe rheumatic mitral valve disease with refractory heart failure. Methods: All women admitted to a single centre from 2011 to 2020 with severe rheumatic mitral valve disease, having recurrent episodes of pulmonary edema on optimal medical therapy and contraindication to percutaneous balloon mitral valvotomy, who underwent concurrent valve replacement (for native valve disease) along with caesarean section, were included. Results: Among 1300 pregnancies with rheumatic heart disease, six underwent the concurrent procedure. All had replacement of mitral valve except one who had both aortic and mitral valve replacements, between 33 and 39 weeks of gestation. There were no maternal deaths, and there was one neonatal loss from late-onset sepsis. Conclusion: Pregnant women with severe rheumatic mitral valve disease with refractory heart failure, unsuitable for minimal access interventions, can be considered for a concurrent valve replacement with caesarean section.
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Pande et al. (2022) studied this question.
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