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November 25, 2003Proceedings of the National Academy of SciencesOpen Access

Interferon-stimulated transcription and innate antiviral immunity require deacetylase activity and histone deacetylase 1

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INInna NusinzonCHCurt M. Horvath

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Nusinzon et al. (2003) studied this question.

synapsesocial.com/papers/6a715c91f44fa9f079df282dhttps://doi.org/10.1073/pnas.2433987100
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The antiviral state induced by alpha interferon and gamma interferon requires transcriptionally active Stat1 protein1996 · 155 citations
  2. 2Nipah Virus V Protein Evades Alpha and Gamma Interferons by Preventing STAT1 and STAT2 Activation and Nuclear Accumulation2002 · 310 citations
  3. 3Interferon Regulatory Factor-2 Regulates Cell Growth through Its Acetylation2003 · 54 citations
  4. 4Histone acetylation and transcriptional regulatory mechanisms1998 · 1,827 citations