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December 19, 2024Cardio-OncologyOpen Access

The AAMR from CVDs with comorbid breast cancer decreased from 2.57 (95% CI 2.50-2.65) in 1999 to 1.20 (95% CI 1.15-1.24) in 2020, with an average annual percent change (AAPC) of -4.3.

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Why the study?

Breast cancer survivors face higher cardiovascular disease risk than non-breast cancer patients, but contemporary data on cardiovascular mortality within this population remain scarce.

Population

74,733 CVD deaths with comorbid breast cancer aged 25 and above in the United States

Comparison

Stratification by age, race, census region, and urbanization level

Design

Population-based retrospective serial cross-sectional study

Authors

YYYong Hao YeoBSBoon‐Jian SanJTJia-Yi Tan

Discussion

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Member takes

Overview

Alerts clinicians to CVD mortality patterns in breast cancer survivors; leaves open targeted prevention trials.

Structured PICO

P
Population
74,733 cardiovascular disease deaths with comorbid breast cancer in patients aged 25 and above in the United States between 1999 and 2020.
O
Outcome
Age-adjusted mortality rates (AAMR) per 100,000 individuals for cardiovascular disease in breast cancer patientshard clinical

Cardiovascular mortality among US breast cancer patients significantly declined from 1999 to 2020, though disparities by race and region persist, and mortality from hypertensive diseases and arrhythmias did not follow this declining trend.

Cite This Study

Yeo et al. (2024) studied this question.

synapsesocial.com/papers/6a715ed0a2d7cf2e39c2c9f6https://doi.org/10.1186/s40959-024-00286-2
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