Why the study?
Acute kidney injury is a common complication after cardiac surgery without pharmacologic prophylaxis, and studies evaluating the renoprotective effect of dexmedetomidine have yielded conflicting conclusions.
Does perioperative dexmedetomidine reduce the incidence of postoperative acute kidney injury in adult patients undergoing cardiac surgery?
Does perioperative dexmedetomidine reduce the incidence of postoperative acute kidney injury in adult patients undergoing cardiac surgery?
Perioperative dexmedetomidine administration significantly reduces the incidence of postoperative acute kidney injury in adults undergoing cardiac surgery.
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Supports dexmedetomidine for AKI prevention in cardiac surgery; strengthens RCT evidence for routine consideration.
Zhao et al. (2021) studied this question.
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