What question did this study set out to answer?

Evaluate trends in Rh antibody incidence among Rh-negative pregnant women and determine remaining causes of maternal sensitisation.

July 8, 1978BMJOpen Access

Prevention of Rh haemolytic disease.

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Evaluate trends in Rh antibody incidence among Rh-negative pregnant women and determine remaining causes of maternal sensitisation.
Regional surveillance tracking the incidence of Rh antibodies in Rh-negative pregnant women from 1970 to 1976.
Evaluation of primary drivers behind ongoing first-affected cases, focusing on delivery, abortion, and antenatal prophylaxis coverage.
Rh antibody incidence in Rh-negative pregnant women decreased by 70% between 1970 and 1976 across both long-standing and newly affected cases.
Persistent new sensitisations stemmed from omitted anti-D administration after normal deliveries and abortions, sensitisation during first pregnancies, and occasional prophylaxis failure.
Universal postpartum and post-abortion anti-D administration could reduce severe Rh haemolytic disease cases to one or two per year in a population of 3 to 4 million.

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Implication

Regional surveillance reports a 70% decrease in Rh antibody incidence among Rh-negative pregnant women, highlighting gaps in anti-D immunoglobulin coverage after delivery and abortion.

Cite This Study

Tovey et al. (1978) studied this question.

synapsesocial.com/papers/6a71622b22b3175134db613f https://doi.org/10.1136/bmj.2.6130.106

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Implication

Regional surveillance reports a 70% decrease in Rh antibody incidence among Rh-negative pregnant women, highlighting gaps in anti-D immunoglobulin coverage after delivery and abortion.

Prevention of Rh haemolytic disease.

Key Points

Discussion

Implication

Cite This Study

Prevention of Rh haemolytic disease.

Key Points

Discussion

Implication

Cite This Study