December 1, 2004Endocrine ReviewsOpen Access

From Hyperglycemia to Diabetic Kidney Disease: The Role of Metabolic, Hemodynamic, Intracellular Factors and Growth Factors/Cytokines

View Full Paper

Ask AI

Bookmark

Population

Patients with type 1 and type 2 diabetes developing diabetic kidney disease

Design

Review

Authors

BSBieke F. SchrijversZealand University Hospital AVAn S. De VrieseUniversity College Ghent AFAllan FlyvbjergUniversity of Copenhagen

Discussion

Member takes

Implication

Offers mechanistic synthesis for DKD; leaves open which targets merit prioritized clinical trials.

Structured PICO

Population

Patients with type 1 (15-25% affected) and type 2 (30-40% affected) diabetes developing diabetic kidney disease

This review summarizes the complex interplay of metabolic, hemodynamic, intracellular, and growth factor pathways in the pathogenesis of diabetic kidney disease and discusses potential therapeutic targets.

Cite This Study

Schrijvers et al. (2004) studied this question.

synapsesocial.com/papers/6a7162fb5d37378ac1de8a8d https://doi.org/10.1210/er.2003-0018

View Full Paper

Ask AI

Bookmark

From Hyperglycemia to Diabetic Kidney Disease: The Role of Metabolic, Hemodynamic, Intracellular Factors and Growth Factors/Cytokines

Discussion

Member takes

Implication

Structured PICO

Cite This Study

From Hyperglycemia to Diabetic Kidney Disease: The Role of Metabolic, Hemodynamic, Intracellular Factors and Growth Factors/Cytokines

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider