Histone acetylation alters the capacity of the H1 histones to condense transcriptionally active/competent chromatin.

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1. 1The β-globin domain in immature chicken erythrocytes: enhanced solubility is coincident with histone hyperacetylation1986 · 25 citations
2. 2Factors affecting nucleosome disassembly by protamines in vitro. Histone hyperacetylation and chromatin structure, time dependence, and the size of the sperm nuclear proteins.1987 · 93 citations
3. 3Erythroid-specific gene chromatin has an altered association with linker histones1988 · 29 citations
4. 4Participation of core histone "tails" in the stabilization of the chromatin solenoid.1982 · 287 citations
5. 5Characterization of the chicken vimentin gene: Single copy gene producing multiple mRNAs1983 · 133 citations