Population
Subjects experiencing long-lasting hypovolemic and other shock conditions
Design
Review
Authors
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Alerts clinicians to cerebral microcirculatory risks in prolonged shock; leaves open targeted interventions to avert irreversible states.
The review highlights that brain function impairment during shock is driven by regional microcirculatory defects and sludge formation, which may contribute to the development of irreversible shock.
Kovach et al. (1976) studied this question.
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