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Does the LF/HF ratio of heart rate variability correlate with the preejection period as a reliable marker of cardiac sympathetic control?
Does the LF/HF ratio of heart rate variability correlate with the preejection period as a reliable marker of cardiac sympathetic control?
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The LF/HF ratio of heart rate variability does not correlate with the preejection period, suggesting it is currently insufficient as a marker of cardiac sympathetic control for epidemiological research.
It has been hypothesized that the ratio of heart rate variability in the low- (LF) and high- (HF) frequency bands may capture variation in cardiac sympathetic control. Here we tested the temporal stability of the LF/HF ratio in 24-h ambulatory recordings and compared this ratio to the preejection period (PEP), an established measure of cardiac sympathetic control. Good temporal stability was found across a period of 3.3 years (.46<r<.78), but the LF/HF ratio did not show the expected negative correlation to PEP, either between or within subjects. We conclude that the evidence to support the LF/HF ratio as a potential marker of cardiac sympathetic control in epidemiology-scaled research is currently insufficient.
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Goedhart et al. (2008) studied this question.
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