Why the study?
Does metformin improve insulin levels and AN score in obese children with hyperinsulinemia and acanthosis nigricans?
Does metformin improve insulin levels and AN score in obese children with hyperinsulinemia and acanthosis nigricans?
Metformin therapy safely lowers fasting and postprandial insulin levels as well as AN scores in obese children with hyperinsulinemia and acanthosis nigricans.
Answers are grounded in this paper and cite their sources.
Should not yet change practice in obese children with hyperinsulinemia; leaves open need for randomized confirmation of benefits.
Tatal 88 obese children with hyperinsulinemia and acanthosis nigricans (AN)were given metformin for 3 and 6 months.The levels of fast insulin,2 h postprandial insulin.and AN score were lower after treatment.Metformin therapy on obese children with hyperinsulinemia and AN was safe.AN score may be an appropriate non-invasive index monitoring disease prognosis.
No takes yet. Share an insight, caveat, or question.
Jiang et al. (2009) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: