Why the study?
The study aimed to evaluate the impact of cardiac magnetic resonance on diagnosis in patients with known or suspected left ventricular noncompaction.
Does cardiac magnetic resonance (CMR) improve diagnostic accuracy in patients with known or suspected left ventricular noncompaction compared to echocardiography?
Does cardiac magnetic resonance (CMR) improve diagnostic accuracy in patients with known or suspected left ventricular noncompaction compared to echocardiography?
CMR is a valuable tool for confirming LVNC and differentiating it from other cardiomyopathies in patients with echocardiographic suspicion.
CMR may alter LVNC diagnosis in referred patients; leaves open effects on management or prognosis.
The aim of this study was to assess the impact of cardiac magnetic resonance (CMR) on the diagnosis in patients with known or suspected left ventricular noncompaction (LVNC). We retrospectively reviewed the medical charts of 12,811 consecutive patients who had CMR studies between 2008 and 2022 in a large tertiary center. We included patients referred for CMR because of known or suspected LVNC. The study sample consisted of 333 patients, 193 (58.0%) male, median age 39.0 (26.8-51.0) years. Among 74 patients fulfilling the echocardiographic LVNC criteria, the diagnosis was confirmed in 54 (73.0%) cases. In 259 patients with ultrasound-based suspicion of LVNC, CMR led to an LVNC diagnosis in 82 (31.7%) patients. In both groups, CMR led to a new diagnosis in 89 cases (10 (13.5%) and 79 (30.5%)). A quantity of 38 (5.4%) patients were diagnosed with dilated cardiomyopathy, 11 (1.4%) patients were diagnosed with hypertrophic cardiomyopathy, and 21 (4.1%) patients were diagnosed with unclassified cardiomyopathy. In four patients with suspected LVNC, a myocardial trabeculation was a secondary result of dilatation due to coronary heart disease. In five cases, valvular heart disease was found. Four patients were diagnosed with athlete's heart. Other diagnoses (arrhythmogenic right ventricular cardiomyopathy, peripartum cardiomyopathy, hypokinetic non-dilated cardiomyopathy, sarcoidosis, amyloidosis, and ventricular septum defect) were found in six patients. CMR is a valuable tool in the evaluation of cardiac muscle and in differentiating LVNC and other cardiac diseases.
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Ojrzyńska et al. (2024) studied this question.
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