Why the study?
Does carotid body resection alter the heart rate response to breath holding in humans?
Population
12 subjects: 5 asymptomatic asthmatic patients with resected carotid bodies and 7 normal control subjects.
Comparison
Prolonged breath holding initiated with single… vs Normal subjects undergoing the same breath…
Design
Other, Breath holding experiments were randomly initiated with single breaths…
Authors
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Supports carotid body mediation of breath-hold bradycardia; leaves open clinical relevance for apnea management.
Does carotid body resection alter the heart rate response to breath holding in humans?
The bradycardia response to breath holding in humans is mediated by the carotid bodies, without which an oxygen tension-dependent tachycardia occurs.
Gross et al. (1976) studied this question.
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