Why the study?
In abdominal aortic aneurysm (AAA), tissue rupture is directly related to wall stress, making the investigation of maximum wall stress necessary to predict aortic rupture.
How do geometric parameters of abdominal aortic aneurysms correlate with peak wall stress in computational simulations?
How do geometric parameters of abdominal aortic aneurysms correlate with peak wall stress in computational simulations?
Computational simulations using patient-derived CT data demonstrate the relationship between AAA geometric parameters and peak wall stress, which may aid in predicting rupture risk.
Geometry influences peak wall stress in AAA models; extends biomechanical insights but leaves clinical translation open.
In abdominal aortic aneurysm (AAA), the rupture of the aortic tissue is directly related to wall stress. Thus, the investigation of maximum wall stress is a necessary procedure to predict the aortic rupture in AAA. In this study, computational simulations were performed to investigate the correlation between peak wall stress (PWS) and AAA geometry. The Holzapfel model and various orientations of the collagen fibers and thicknesses of the layers of the aorta were employed in the simulation. The material constants used in the Holzapfel model were estimated from the examination and analysis of the biaxial tensile test results of the normal abdominal aorta and AAA. The aneurysm diameter, height, neck angle, and iliac angle were selected as geometric factors affecting the AAA rupture. In addition, a simulation scenario was conceived and created based on the measurement results using the computed tomography data of patients with AAA. Accordingly, the correlation between the PWS and AAA geometry was estimated.
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You et al. (2021) studied this question.
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