What question did this study set out to answer?

Evaluate a rapid clinical diffusion tensor imaging protocol for human forearm muscles and assess the test-retest reproducibility of six quantitative diffusion parameters.

August 19, 2010Magnetic Resonance in MedicineOpen Access

Reproducibility of diffusion tensor imaging in human forearm muscles at 3.0 T in a clinical setting

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Authors

MFMartijn FroelingUtrecht University JOJos OudemanUtrecht University SBSandra BergUniversity of Leeds

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Implication

Test-retest study demonstrates substantial reproducibility of forearm diffusion tensor imaging in healthy volunteers, indicating its feasibility for clinical longitudinal assessments.

Key Points

Evaluate a rapid clinical diffusion tensor imaging protocol for human forearm muscles and assess the test-retest reproducibility of six quantitative diffusion parameters.
Acquired 3.0 T diffusion tensor images of the right forearm in 10 healthy volunteers across two scanning sessions spaced one week apart using a 7-minute 40-second protocol.
Assessed reproducibility of tensor eigenvalues (λ1, λ2, λ3), mean diffusivity, fractional anisotropy, and ellipsoid eccentricity across three regions of interest: whole muscle volume, flexor digitorum profundus, and extensor digitorum.
Quantified agreement using Bland-Altman plots, repeatability index, coefficient of repeatability, and intraclass correlation coefficients.
Bland-Altman analysis revealed good overall agreement between scans across the two test sessions.
Intraclass correlation coefficients demonstrated substantial agreement (0.59 < ICC < 0.92) across all six parameters for whole muscle volume and the flexor digitorum profundus.
Extensor digitorum measurements showed only fair agreement (0.18 < ICC < 0.64), highlighting that reproducibility varies depending on the anatomical region evaluated.

Cite This Study

Froeling et al. (2010) studied this question.

synapsesocial.com/papers/6a717d12fe4101aa97e09896 https://doi.org/10.1002/mrm.22477

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Implication

Test-retest study demonstrates substantial reproducibility of forearm diffusion tensor imaging in healthy volunteers, indicating its feasibility for clinical longitudinal assessments.

Reproducibility of diffusion tensor imaging in human forearm muscles at 3.0 T in a clinical setting

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Implication

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Cite This Study

Reproducibility of diffusion tensor imaging in human forearm muscles at 3.0 T in a clinical setting

Discussion

Member takes

Implication

Key Points

Cite This Study

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