Population
Experimental models of kidney disease, subtotal nephrectomy, and hypertension, including ACE2 knockout animals
Design
Review
Authors
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ACE2 may protect kidneys and BP in RAS activation; leaves open clinical translation pending human trials.
ACE2 plays a protective role in the kidney and in blood pressure regulation by counterbalancing the effects of angiotensin II.
Koı̈tka et al. (2008) studied this question.
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