Why the study?
Does anorexia nervosa alter autonomic cardiac control in response to postural change compared to healthy controls?
Does anorexia nervosa alter autonomic cardiac control in response to postural change compared to healthy controls?
Anorexia nervosa is associated with alterations in autonomic cardiac control, characterized by reduced heart rate variability and altered spectral power responses to postural changes.
Anorexia nervosa was associated with reduced standing HRV; leaves open prognostic value and need for prospective studies.
The aim of this study was to investigate the response of autonomic cardiac control to postural change using spectral analysis, in patients with anorexia nervosa. Spectral components of total variability as well as of low and high frequencies were analyzed for 17 anorexic patients with mean body mass index (14.9 +/- 1.9) kg/m2 and for 9 healthy age-matched women with body mass index (20.3 +/- 1.7) kg/m2 , in supine and standing postures. During standing posture, increased heart rate in all subjects was accompanied by the decrease in total variability and high frequency spectral powers. In supine posture, anorexic patients demonstrated the reduced low frequency spectral power. Compared to control women, during standing posture anorexic patients showed higher heart rate, reduced total variability and high frequency spectral powers. Statistically significant correlation was noticed between body mass index and spectral power of low frequency in both supine and standing posture. Alterations in autonomic cardiac control induced by anorexia nervosa could be estimated by spectral analysis of heart period variability.
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Platiša et al. (2005) studied this question.
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