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April 1, 1993The Journal of PhysiologyOpen Access

Stimulation of the KATP channel by ADP and diazoxide requires nucleotide hydrolysis in mouse pancreatic beta‐cells.

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Authors

OLOlof LarssonNvidia (United Kingdom)CÄCarina ÄmmäläNovo Nordisk (Finland)KBKrister BokvistSanofi (Germany)

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Larsson et al. (1993) studied this question.

synapsesocial.com/papers/6a7187f7a528af2d65c41b95https://doi.org/10.1113/jphysiol.1993.sp019598
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1ATP‐sensitive K+ channels in rat pancreatic beta‐cells: modulation by ATP and Mg2+ ions.1989 · 154 citations
  2. 2Cytosolic ADP enhances the sensitivity to tolbutamide of ATP‐dependent K+ channels from pancreatic B‐cells1988 · 92 citations
  3. 3Dual effects of diazoxide on ATP‐K+ currents recorded from an insulin‐secreting cell line1989 · 93 citations
  4. 4Diazoxide and D600 Inhibition of Insulin Release: Distinct Mechanisms Explain the Specificity for Different Stimuli1982 · 100 citations
  5. 5ATP-sensitive K+-channel run-down is Mg2+ dependent1990 · 67 citations