Why the study?
Are ventilatory responses to hypoxia, hypercapnia, and exercise altered in patients with idiopathic hyperventilation compared to controls?
Population
39 patients with idiopathic hyperventilation (IH) and 23 control subjects
Comparison
Exposure to isocapnic-hypoxia… vs 23 healthy control subjects
Design
Case-control
Authors
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May sustain dyspnea in idiopathic hyperventilation; hypothesis-generating for chemoreflex mechanisms and needs prospective trials.
Are ventilatory responses to hypoxia, hypercapnia, and exercise altered in patients with idiopathic hyperventilation compared to controls?
Patients with idiopathic hyperventilation exhibit a sustained hyperventilatory and dyspneic drive that is maintained during exercise and may involve peripheral chemoreflex contributions.
Jack et al. (2004) studied this question.
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