Why the study?
Do acute changes in shear stress alter peripheral conduit artery mechanics and smooth muscle tone in healthy humans?
Population
Healthy volunteers (n=12 for distal flow arrest, n=18 for hand skin heating), mean age 25 +/- 1 years.
Comparison
Acute changes in shear stress induced by distal… vs Baseline measurements prior to flow arrest or…
Design
Other
Authors
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Acute flow changes modulate conduit artery mechanics in healthy adults; extends mechanistic evidence but leaves open disease relevance.
Do acute changes in shear stress alter peripheral conduit artery mechanics and smooth muscle tone in healthy humans?
Acute changes in blood flow and shear stress directly regulate arterial smooth muscle tone and stiffness in human peripheral conduit arteries.
Joannidès et al. (2001) studied this question.
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